STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_13425COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (186 aa)    
Predicted Functional Partners:
DegS
COG4564 Signal transduction histidine kinase.
 
 
 0.748
RAM_27550
COG4585 Signal transduction histidine kinase.
 
 
 0.743
RAM_28065
COG4585 Signal transduction histidine kinase.
 
 
 0.734
RAM_18085
Two-component system sensor kinase; COG4585 Signal transduction histidine kinase.
 
 
 0.727
RAM_16025
COG4585 Signal transduction histidine kinase.
 
 
 0.718
RAM_00840
Two-component system sensor kinase; COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific.
 
 
 0.715
Rnd
COG0349 Ribonuclease D.
       0.710
RAM_43410
COG4585 Signal transduction histidine kinase.
 
 
 0.703
RAM_18055
COG4585 Signal transduction histidine kinase.
 
 
 0.688
RAM_40540
COG4585 Signal transduction histidine kinase.
 
 
 0.671
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.