STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_13555Hypothetical protein; COG0346 Lactoylglutathione lyase and related lyases. (145 aa)    
Predicted Functional Partners:
RAM_13560
COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.
       0.773
RAM_13550
COG3795 Uncharacterized protein conserved in bacteria.
       0.752
RAM_02110
Riboflavin biosynthesis protein RibD; COG0262 Dihydrofolate reductase.
 
  
 0.535
RAM_19000
Riboflavin biosynthesis protein RibD.
 
  
 0.516
RAM_38285
Deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase.
 
  
 0.516
RAM_13545
Hypothetical protein.
       0.480
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.469
RAM_06605
Hypothetical protein; COG0262 Dihydrofolate reductase.
 
  
 0.442
RAM_04910
Deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase.
 
  
 0.433
RAM_44225
Riboflavin biosynthesis protein; COG0262 Dihydrofolate reductase.
 
  
 0.425
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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