| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CysG | YcaJ | RAM_25450 | RAM_13770 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. | 0.566 |
| CysG | nadE | RAM_25450 | RAM_06165 | uroporphyrin-III C-methyltransferase/precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.405 |
| DnaN | DnaN-2 | RAM_00010 | RAM_45335 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). | 0.919 |
| DnaN | RAM_06255 | RAM_00010 | RAM_06255 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG0210 Superfamily I DNA and RNA helicases. | 0.951 |
| DnaN | RecQ | RAM_00010 | RAM_15275 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG0514 Superfamily II DNA helicase. | 0.596 |
| DnaN | RecQ-2 | RAM_00010 | RAM_21345 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG0514 Superfamily II DNA helicase. | 0.596 |
| DnaN | RecQ-3 | RAM_00010 | RAM_34350 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COG0514 Superfamily II DNA helicase. | 0.646 |
| DnaN | YcaJ | RAM_00010 | RAM_13770 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. | 0.707 |
| DnaN | dinB-4 | RAM_00010 | RAM_32165 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.570 |
| DnaN-2 | DnaN | RAM_45335 | RAM_00010 | COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.919 |
| DnaN-2 | RAM_06255 | RAM_45335 | RAM_06255 | COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). | COG0210 Superfamily I DNA and RNA helicases. | 0.932 |
| DnaN-2 | RecQ | RAM_45335 | RAM_15275 | COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). | COG0514 Superfamily II DNA helicase. | 0.596 |
| DnaN-2 | RecQ-2 | RAM_45335 | RAM_21345 | COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). | COG0514 Superfamily II DNA helicase. | 0.596 |
| DnaN-2 | RecQ-3 | RAM_45335 | RAM_34350 | COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). | COG0514 Superfamily II DNA helicase. | 0.646 |
| DnaN-2 | YcaJ | RAM_45335 | RAM_13770 | COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). | Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. | 0.707 |
| DnaN-2 | dinB-4 | RAM_45335 | RAM_32165 | COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.570 |
| RAM_06255 | DnaN | RAM_06255 | RAM_00010 | COG0210 Superfamily I DNA and RNA helicases. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.951 |
| RAM_06255 | DnaN-2 | RAM_06255 | RAM_45335 | COG0210 Superfamily I DNA and RNA helicases. | COG0592 DNA polymerase sliding clamp subunit (PCNA homolog). | 0.932 |
| RAM_06255 | RecQ-3 | RAM_06255 | RAM_34350 | COG0210 Superfamily I DNA and RNA helicases. | COG0514 Superfamily II DNA helicase. | 0.475 |
| RAM_06255 | YcaJ | RAM_06255 | RAM_13770 | COG0210 Superfamily I DNA and RNA helicases. | Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. | 0.753 |
