STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mltGAminodeoxychorismate lyase-like protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (759 aa)    
Predicted Functional Partners:
aroE
COG0169 Shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family.
  
    0.941
RuvX
Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
  
    0.892
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
    0.826
RAM_45425
Penicillin binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
   
 0.805
RAM_15390
Penicillin-binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
   
 0.795
FtsW-2
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
 
   
 0.674
FolP-5
COG0294 Dihydropteroate synthase and related enzymes.
  
  
 0.668
Pbp
Penicillin binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
   
 0.651
MrcB
Penicillin binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
   
 0.639
RAM_09250
Glycosyl transferase family 51; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
   
 0.627
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: medium (64%) [HD]