| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FruA | FruB | RAM_22910 | RAM_22915 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | 0.999 |
| FruA | ManX-2 | RAM_22910 | RAM_06950 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | Mannose/sorbose-specific IIA subunit of PTS system; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. | 0.702 |
| FruA | NagE | RAM_22910 | RAM_13855 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | 0.872 |
| FruA | NagE-2 | RAM_22910 | RAM_13865 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | PTS system, glucose/maltose/N-acetylglucosamine-specific IIB component; COG1264 Phosphotransferase system IIB components. | 0.866 |
| FruA | NagE-3 | RAM_22910 | RAM_13870 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | PTS system, glucose/maltose/N-acetylglucosamine-specific IIA component; COG2190 Phosphotransferase system IIA components. | 0.860 |
| FruA | PtsI | RAM_22910 | RAM_22930 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria). | 0.981 |
| FruA | PtsI-2 | RAM_22910 | RAM_47770 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | Phosphotransferase system EI component; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.961 |
| FruA | RAM_11940 | RAM_22910 | RAM_11940 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | Hypothetical protein. | 0.907 |
| FruA | RAM_13850 | RAM_22910 | RAM_13850 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | Phosphocarrier protein. | 0.991 |
| FruA | RAM_22905 | RAM_22910 | RAM_22905 | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | COG1925 Phosphotransferase system, HPr-related proteins. | 0.997 |
| FruB | FruA | RAM_22915 | RAM_22910 | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | 0.999 |
| FruB | ManX-2 | RAM_22915 | RAM_06950 | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | Mannose/sorbose-specific IIA subunit of PTS system; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. | 0.650 |
| FruB | NagE | RAM_22915 | RAM_13855 | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. | 0.652 |
| FruB | NagE-2 | RAM_22915 | RAM_13865 | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | PTS system, glucose/maltose/N-acetylglucosamine-specific IIB component; COG1264 Phosphotransferase system IIB components. | 0.641 |
| FruB | NagE-3 | RAM_22915 | RAM_13870 | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | PTS system, glucose/maltose/N-acetylglucosamine-specific IIA component; COG2190 Phosphotransferase system IIA components. | 0.668 |
| FruB | PtsI | RAM_22915 | RAM_22930 | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria). | 0.896 |
| FruB | PtsI-2 | RAM_22915 | RAM_47770 | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | Phosphotransferase system EI component; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.777 |
| FruB | RAM_13850 | RAM_22915 | RAM_13850 | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | Phosphocarrier protein. | 0.967 |
| FruB | RAM_22905 | RAM_22915 | RAM_22905 | PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). | COG1925 Phosphotransferase system, HPr-related proteins. | 0.990 |
| ManX-2 | FruA | RAM_06950 | RAM_22910 | Mannose/sorbose-specific IIA subunit of PTS system; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. | PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB. | 0.702 |