STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NagECOG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. (410 aa)    
Predicted Functional Partners:
NagE-3
PTS system, glucose/maltose/N-acetylglucosamine-specific IIA component; COG2190 Phosphotransferase system IIA components.
 
 0.984
RAM_13850
Phosphocarrier protein.
 
 
 0.983
NagA
COG1820 N-acetylglucosamine-6-phosphate deacetylase.
 
  
 0.966
RAM_22905
COG1925 Phosphotransferase system, HPr-related proteins.
 
 
 0.953
murQ
N-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
 
 
 0.945
NagE-2
PTS system, glucose/maltose/N-acetylglucosamine-specific IIB component; COG1264 Phosphotransferase system IIB components.
 
  
 0.935
FruA
PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB.
  
  
 0.872
RAM_13860
COG2188 Transcriptional regulators.
 
  
 0.848
PtsI-2
Phosphotransferase system EI component; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
 0.777
PtsI
COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria).
  
 0.773
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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