STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_14145COG3000 Sterol desaturase. (286 aa)    
Predicted Functional Partners:
CrtB
COG1562 Phytoene/squalene synthetase.
  
 
 0.683
CrtB-2
COG1562 Phytoene/squalene synthetase.
  
 
 0.683
RAM_14150
COG1309 Transcriptional regulator.
 
     0.608
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.587
RAM_20890
Fused protein kinase and phosphatase containing multi-sensor domain; COG2202 FOG: PAS/PAC domain.
  
    0.574
PaaE-2
Phenylacetic acid degradation oxidoreductase; COG3239 Fatty acid desaturase.
 
  
 0.536
RAM_30220
Two-component system sensor kinase; COG2202 FOG: PAS/PAC domain.
   
 
 0.526
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
    
   0.509
RAM_01960
Signal transduction protein containing EAL, PAS and GGDEF domain; COG2202 FOG: PAS/PAC domain.
  
  
 0.507
RAM_02995
Signal sensor protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
    0.497
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.