STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
RAM_14315Peptidylprolyl isomerase; COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1. (186 aa)    
Predicted Functional Partners:
RAM_31455
COG5126 Ca2+-binding protein (EF-Hand superfamily).
   
 0.776
RAM_14310
COG3973 Superfamily I DNA and RNA helicases.
     
 0.775
infA
Translation initiation factor IF-1 infA; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.706
RAM_34185
Probable chaperone protein; COG0326 Molecular chaperone, HSP90 family.
  
 0.706
infA-2
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.706
RAM_05625
Hypothetical protein.
   
 
 0.684
LysC
COG0527 Aspartokinases; Belongs to the aspartokinase family.
    
   0.664
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
   
 0.660
RAM_39810
Hypothetical protein.
   
 0.617
RAM_14300
Hypothetical protein.
       0.589
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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