STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
SufSCysteine desulfurase/selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (429 aa)    
Predicted Functional Partners:
NifU
Nitrogen fixation protein NifU; COG0822 NifU homolog involved in Fe-S cluster formation.
 
 
 0.991
SufC
COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
 
  
 0.967
SufB
COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
 
 0.958
SufD
COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
 
 0.957
RAM_14405
COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.
 
  
 0.956
IscS-2
Aminotransferase class V/cysteine desulfurase; COG0520 Selenocysteine lyase.
  
  
 
0.920
TrxB-4
COG0492 Thioredoxin reductase.
 
 
  0.920
TrxB
Thioredoxin reductase; COG0784 FOG: CheY-like receiver.
  
 
 0.909
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
    
 0.907
MetB
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
    
 0.904
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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