STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_14570COG1132 ABC-type multidrug transport system, ATPase and permease components. (612 aa)    
Predicted Functional Partners:
AcuC
Acetoin utilization protein AcuC; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
 
 0.596
arc
COG0464 ATPases of the AAA+ class.
  
 
  0.563
RAM_23745
COG0522 Ribosomal protein S4 and related proteins.
  
 
 0.550
DnaK-2
Molecular chaperone DnaK; COG4249 Uncharacterized protein containing caspase domain; Belongs to the heat shock protein 70 family.
 
 0.530
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.524
mshD
Acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
     0.522
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
  
 
 0.518
RAM_26330
Chaperone protein DnaK-like protein; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
  
 0.515
RAM_14565
COG1846 Transcriptional regulators.
     
 0.498
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
  
 
 0.486
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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