STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_14610Diguanylate cyclase/phosphodiesterase; COG2199 FOG: GGDEF domain. (605 aa)    
Predicted Functional Partners:
RAM_01960
Signal transduction protein containing EAL, PAS and GGDEF domain; COG2202 FOG: PAS/PAC domain.
 
 
0.970
RAM_14510
Hypothetical protein; COG2200 FOG: EAL domain.
 
 
 0.955
RAM_23045
Two-component system sensor kinase; COG2770 FOG: HAMP domain.
  
 
 0.944
RAM_20890
Fused protein kinase and phosphatase containing multi-sensor domain; COG2202 FOG: PAS/PAC domain.
  
 
 0.918
RAM_34820
Two-component system sensor kinase; COG2770 FOG: HAMP domain.
  
 
 0.895
RAM_02995
Signal sensor protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 
 
0.881
RAM_46695
GGDEF domain-containing protein; COG2199 FOG: GGDEF domain.
 
 
 0.863
RAM_30220
Two-component system sensor kinase; COG2202 FOG: PAS/PAC domain.
  
 
 0.842
DevS-2
Two-component system sensor kinase; COG2203 FOG: GAF domain.
  
 
 0.766
RAM_39020
Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.
     
 0.738
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.