STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MviNMviN-like protein; COG0728 Uncharacterized membrane protein, putative virulence factor. (586 aa)    
Predicted Functional Partners:
RAM_00285
FHA domain-containing protein; COG1716 FOG: FHA domain.
 
 
 
 0.905
FtsW
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
 
  
 0.697
RAM_25405
FHA domain-containing protein; COG1716 FOG: FHA domain.
 
 
 
 0.681
RAM_47945
Integral membrane protein MviN; COG0515 Serine/threonine protein kinase.
 
      0.670
RAM_00280
FHA domain-containing protein; COG1716 FOG: FHA domain.
 
 
 
 0.622
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
   
 0.557
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
    0.556
FtsW-2
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
 
  
 0.538
HolA
Hypothetical protein; COG1466 DNA polymerase III, delta subunit.
 
  
 0.538
FtsI
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
   
 0.531
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.