STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YfiHMulti-copper oxidoreductase; Belongs to the multicopper oxidase YfiH/RL5 family. (229 aa)    
Predicted Functional Partners:
RAM_15035
Pyridoxal-5'-phosphate dependent enzyme class III; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.969
Hpt
COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
  0.923
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.906
Apt
COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins.
    
  0.906
PunA
COG0005 Purine nucleoside phosphorylase.
    
  0.905
Add
COG1816 Adenosine deaminase.
    
 0.902
Add-2
COG1816 Adenosine deaminase.
    
 0.902
surE
5'(3')-nucleotidase/polyphosphatase; COG0496 Predicted acid phosphatase.
    
  0.902
GuaD
Deaminase; COG0590 Cytosine/adenosine deaminases.
    
  0.902
Add-3
COG1816 Adenosine deaminase.
    
 0.902
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.