STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_15120Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (403 aa)    
Predicted Functional Partners:
HmgA
COG3508 Homogentisate 1,2-dioxygenase.
 
  
 0.958
RAM_41590
COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
 
  
 0.935
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.844
sdhA
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 
  0.822
sdhA-2
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 
  0.822
sdhA-3
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
  
 
  0.822
SdhB
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
 
  0.809
SdhB-2
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
 
  0.809
SdhB-3
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
 
  0.809
SdhC
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 
  0.807
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.