STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
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[Homology]
Score
RAM_15390Penicillin-binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein). (684 aa)    
Predicted Functional Partners:
RAM_00265
Peptidoglycan glycosyl transferase; COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 
 0.829
FtsW-2
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
 
 
 
 0.802
mltG
Aminodeoxychorismate lyase-like protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
 
   
 0.735
FtsI
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 
 0.735
RelA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
   
 0.699
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
   
 0.692
FtsW
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
 
 
 
 0.690
nusG
Transcription antiterminator NusG; Participates in transcription elongation, termination and antitermination.
 
   
 0.677
RAM_10380
Penicillin-binding protein, transpeptidase; COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 
 0.672
RAM_04085
COG0739 Membrane proteins related to metalloendopeptidases.
  
   
 0.653
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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