STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_156952-hydroxyhepta-2,4-diene-1,7-dioate isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (283 aa)    
Predicted Functional Partners:
RAM_15690
Amidohydrolase; COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold.
 
     0.890
RAM_15685
Hypothetical protein.
       0.780
RAM_15680
COG1691 NCAIR mutase (PurE)-related proteins.
       0.779
RAM_15700
Mandelate racemase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.768
RAM_15705
COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
 
 0.707
HmgA
COG3508 Homogentisate 1,2-dioxygenase.
  
  
 0.581
RAM_15725
Oxidoreductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).
 
    0.573
RAM_09315
Mandelate racemase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.557
RAM_09350
Amidohydrolase; COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold.
 
     0.541
RAM_15710
COG1879 ABC-type sugar transport system, periplasmic component.
       0.525
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.