STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_16225D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa)    
Predicted Functional Partners:
RAM_16220
COG4289 Uncharacterized protein conserved in bacteria.
 
     0.927
RAM_16230
COG0395 ABC-type sugar transport system, permease component.
 
     0.820
RAM_16240
ABC transporter substrate-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.
 
     0.723
LacI-6
COG1349 Transcriptional regulators of sugar metabolism.
 
    0.699
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.680
RAM_08530
Oxidoreductase; COG0673 Predicted dehydrogenases and related proteins.
 
   
 0.649
RAM_35600
Xylose isomerase; COG1082 Sugar phosphate isomerases/epimerases.
 
     0.647
RAM_16235
COG1175 ABC-type sugar transport systems, permease components.
 
     0.617
RAM_35595
Hypothetical protein.
 
    0.596
MalZ-2
Alpha-glucosidase; COG0366 Glycosidases.
       0.594
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.