STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LacI-6COG1349 Transcriptional regulators of sugar metabolism. (369 aa)    
Predicted Functional Partners:
FruA
PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB.
  
  
 0.844
RAM_16220
COG4289 Uncharacterized protein conserved in bacteria.
 
     0.831
RAM_16245
Heparinase II/III family protein.
 
    0.823
RAM_16240
ABC transporter substrate-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.
 
   
 0.822
LacI-11
COG1609 Transcriptional regulators.
  
   
 0.718
RAM_16225
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
     0.696
RAM_16260
COG1609 Transcriptional regulators.
  
   
 0.696
RAM_16235
COG1175 ABC-type sugar transport systems, permease components.
 
   
 0.642
LacI-25
COG1609 Transcriptional regulators.
  
   
 0.621
LacI-7
Transcriptional regulator, LacI family; COG1609 Transcriptional regulators.
  
   
 0.586
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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