STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_16290Formate dehydrogenase alpha subunit, selenocysteine-containing protein; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (871 aa)    
Predicted Functional Partners:
RAM_16285
COG0437 Fe-S-cluster-containing hydrogenase components 1.
 
 
 0.997
RAM_16295
Formate dehydrogenase alpha subunit, selenocysteine-containing protein; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.
     0.991
RAM_29330
COG0437 Fe-S-cluster-containing hydrogenase components 1.
 
 
 0.989
RAM_29320
Formate dehydrogenase alpha subunit, selenocysteine-containing protein; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.
  
 0.983
RAM_16280
Polysulphide reductase NrfD.
 
     0.951
NuoF-2
COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
  
 
 0.923
RAM_29325
Formate dehydrogenase alpha subunit, selenocysteine-containing protein; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
0.918
RAM_33650
COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.
     
 0.903
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.900
frc
Formyl-coenzyme A transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.
     
  0.900
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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