STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhA-3COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (640 aa)    
Predicted Functional Partners:
SdhC-2
Succinate dehydrogenase cytochrome b-556 subunit.
 
 0.999
SdhB-3
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
 
 0.998
SdhC
COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 0.991
SdhD
COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.
  
 0.986
SdhB
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
 0.979
SdhB-2
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
 0.979
NuoF-2
COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
  
 
 0.941
RAM_13045
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
 
 0.928
RAM_40455
Arylmalonate decarboxylase; COG3473 Maleate cis-trans isomerase.
   
 
  0.903
sdhA
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
     
 
0.900
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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