STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_16635fatty-acyl-CoA synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (511 aa)    
Predicted Functional Partners:
RAM_18760
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
0.835
AcsA-2
COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
 
0.808
RifB
COG3321 Polyketide synthase modules and related proteins.
  
 0.807
RAM_16615
Amidohydrolase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.
 
   
 0.800
RAM_16640
COG1062 Zn-dependent alcohol dehydrogenases, class III.
 
  
 0.799
FadB
COG1250 3-hydroxyacyl-CoA dehydrogenase.
  
  
 0.797
PaaG-9
COG1024 Enoyl-CoA hydratase/carnithine racemase.
  
   0.797
RAM_18765
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 0.789
RAM_27510
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 0.789
RAM_16645
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
   0.753
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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