STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_16840COG3300 MHYT domain (predicted integral membrane sensor domain). (254 aa)    
Predicted Functional Partners:
RAM_16830
COG0642 Signal transduction histidine kinase.
 
     0.803
RAM_16835
Hypothetical protein.
 
     0.787
RAM_39020
Two-component system sensor kinase; COG0642 Signal transduction histidine kinase.
  
  
 0.507
RAM_01960
Signal transduction protein containing EAL, PAS and GGDEF domain; COG2202 FOG: PAS/PAC domain.
   
 0.436
RAM_39015
Two-component system response regulator; COG0784 FOG: CheY-like receiver.
  
    0.426
TrxB
Thioredoxin reductase; COG0784 FOG: CheY-like receiver.
  
    0.404
RAM_42700
Hypothetical protein.
   
    0.400
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.