STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_17130COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (525 aa)    
Predicted Functional Partners:
RAM_04760
Acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
 
 0.979
RAM_14680
acyl-CoA carboxylase alpha chain; COG0439 Biotin carboxylase.
 
 0.979
RAM_40715
Acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.
 
 0.978
Mce
methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases.
 
 
 0.975
RAM_41510
COG1960 Acyl-CoA dehydrogenases.
  
 
 0.921
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.917
Acs-2
COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
 0.915
Acs-3
COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
 0.915
PrpE
COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
 0.914
MmsA
COG1012 NAD-dependent aldehyde dehydrogenases.
   
 0.911
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.