STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_17260Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (640 aa)    
Predicted Functional Partners:
RAM_04275
COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III.
   
   0.732
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
   
   0.732
RAM_11480
COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III.
   
   0.732
RAM_39585
Beta-lactamase; COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III.
   
   0.732
NuoF-2
COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
   
    0.685
NuoF
NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
   
    0.537
RAM_30460
Respiratory-chain NADH dehydrogenase-related protein; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit.
   
    0.537
pheT
phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.529
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
    
 
 0.492
RAM_17265
X-Pro dipeptidyl-peptidase; COG2936 Predicted acyl esterases.
       0.492
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.