STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_17770COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (510 aa)    
Predicted Functional Partners:
RAM_17765
COG1309 Transcriptional regulator.
 
     0.839
RAM_18760
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
0.829
RAM_17775
Luciferase-like protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
 
     0.817
RAM_18765
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 0.805
RAM_27510
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 0.805
RAM_17780
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
   0.752
RAM_15925
COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
     0.690
RAM_18750
Hypothetical protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 0.560
RAM_18740
Non-ribosomal peptide synthetase/polyketide synthase; COG3321 Polyketide synthase modules and related proteins.
  
0.559
RifB
COG3321 Polyketide synthase modules and related proteins.
 
 0.551
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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