STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_17835LuxR family transcriptional regulator fused with ATPase domain; COG2771 DNA-binding HTH domain-containing proteins. (916 aa)    
Predicted Functional Partners:
RAM_17830
Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.
 
    0.615
YaeR
Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.
  
     0.554
RAM_17900
Transmembrane anti-sigma factor.
  
    0.491
RAM_28795
Hypothetical protein.
  
     0.482
RAM_20890
Fused protein kinase and phosphatase containing multi-sensor domain; COG2202 FOG: PAS/PAC domain.
  
 
 0.468
Adh-5
COG1064 Zn-dependent alcohol dehydrogenases.
       0.433
RAM_06965
SARP family transcriptional regulator fused with ATPase domain; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 
 0.430
RAM_17840
Heavy metal transport/detoxification protein; COG2608 Copper chaperone.
       0.428
PdhD-4
COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
       0.425
RAM_04505
COG4758 Predicted membrane protein.
 
    0.424
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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