STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CheBCheB methylesterase; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain. (345 aa)    
Predicted Functional Partners:
CheR
COG1352 Methylase of chemotaxis methyl-accepting proteins.
  
 0.988
RAM_18250
PAS domain-containing sensor protein; COG2202 FOG: PAS/PAC domain.
 
  
 0.954
CheR-2
COG1352 Methylase of chemotaxis methyl-accepting proteins.
  
 0.948
RAM_23045
Two-component system sensor kinase; COG2770 FOG: HAMP domain.
 
 
 0.788
RAM_10000
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.725
RAM_39015
Two-component system response regulator; COG0784 FOG: CheY-like receiver.
 
 
 0.719
RAM_01960
Signal transduction protein containing EAL, PAS and GGDEF domain; COG2202 FOG: PAS/PAC domain.
  
 0.690
RAM_34820
Two-component system sensor kinase; COG2770 FOG: HAMP domain.
 
 
 0.668
RAM_18245
Hypothetical protein.
 
     0.656
RAM_20890
Fused protein kinase and phosphatase containing multi-sensor domain; COG2202 FOG: PAS/PAC domain.
 
  
 0.649
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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