STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_19250COG1740 Ni,Fe-hydrogenase I small subunit. (315 aa)    
Predicted Functional Partners:
RAM_19320
COG0374 Ni,Fe-hydrogenase I large subunit.
 
 0.997
RAM_19255
Thioredoxin-like protein.
 
   
 0.952
RAM_19260
Hypothetical protein.
 
   
 0.951
HypF
COG0068 Hydrogenase maturation factor.
 
 
 
 0.926
RAM_19325
COG1740 Ni,Fe-hydrogenase I small subunit.
  
  
 
0.901
RAM_19295
Peptidase M52/hydrogen uptake protein; COG0680 Ni,Fe-hydrogenase maturation factor.
 
  
 0.859
RAM_19300
Hypothetical protein; COG0474 Cation transport ATPase.
 
  
 0.839
HypC
Hydrogenase assembly chaperone HypC/HupF; COG0298 Hydrogenase maturation factor.
 
 
 0.823
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.813
HypD
Hydrogenase isoenzymes formation protein HypD; COG0409 Hydrogenase maturation factor.
 
  
 0.808
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.