STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PaaK-2phenylacetate-CoA ligase; COG1541 Coenzyme F390 synthetase. (441 aa)    
Predicted Functional Partners:
PaaI
COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.
 
 
 0.975
PaaB
Phenylacetic acid degradation protein PaaB; COG3460 Uncharacterized enzyme of phenylacetate metabolism.
 
 
 0.961
paaA
phenylacetate-CoA oxygenase subunit PaaA.
 
 
 0.960
PaaD
Phenylacetic acid degradation protein PaaD; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.
 
  
 0.959
PaaC
Phenylacetic acid degradation protein PaaC.
 
 
 0.957
PaaE
Phenylacetic acid degradation oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
 
 
 0.939
PaaK
phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
  
  
 
0.928
PaaK-3
phenylacetate-CoA ligase; COG1541 Coenzyme F390 synthetase.
  
  
  0.916
AmiE
Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.
    
 0.905
AmiE-2
Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.
    
 0.905
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.