STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FadD-5COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (529 aa)    
Predicted Functional Partners:
RAM_18760
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
0.824
RifB
COG3321 Polyketide synthase modules and related proteins.
  
 0.807
RAM_19695
Hypothetical protein; COG0183 Acetyl-CoA acetyltransferase.
  
 
 0.802
RAM_18765
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 0.789
RAM_27510
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 0.789
RAM_19700
Hypothetical protein; COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon.
  
    0.780
RAM_11380
Fatty acid CoA ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
     0.769
RAM_19705
Dehydratase; COG2030 Acyl dehydratase.
     
 0.765
RAM_15925
COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
     0.757
RAM_19710
COG2186 Transcriptional regulators.
     
 0.736
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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