close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FolP-2COG0294 Dihydropteroate synthase and related enzymes. (305 aa)    
Predicted Functional Partners:
FolK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
 
 
 0.993
FolB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.986
RAM_34460
COG0285 Folylpolyglutamate synthase.
 
 0.979
PabC
4-amino-4-deoxychorismate lyase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
  
 
 0.917
folE-2
COG0302 GTP cyclohydrolase I.
  
 0.820
folE
COG0302 GTP cyclohydrolase I.
 
  
 0.814
RAM_19755
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.774
PabB
COG0147 Anthranilate/para-aminobenzoate synthases component I.
 
  
 0.598
PabA
COG0512 Anthranilate/para-aminobenzoate synthases component II.
 
  
 0.532
RAM_19750
COG2186 Transcriptional regulators.
       0.530
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.