STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LacCTagatose 6-phosphate kinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB). (310 aa)    
Predicted Functional Partners:
FruA
PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB.
 
  
 0.996
FbaA
Fructose-bisphosphate aldolase, class II; COG0191 Fructose/tagatose bisphosphate aldolase.
  
 0.943
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
 0.933
FruB
PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
  
 0.857
FruR-2
COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.815
AgaR
COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.797
FruR
COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.780
FruR-3
COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.771
RAM_03765
COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.755
GlpR
COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.750
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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