STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_20065Formyl transferase-like protein; COG0223 Methionyl-tRNA formyltransferase. (563 aa)    
Predicted Functional Partners:
RsmB
Ribosomal RNA small subunit methyltransferase B; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.958
RAM_18760
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.956
RAM_18765
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.956
RAM_27510
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.956
RifA
Rifamycin polyketide synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
 0.836
RAM_20005
Polyketide synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
 0.828
RifB
COG3321 Polyketide synthase modules and related proteins.
  
 0.795
RAM_18750
Hypothetical protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.778
RAM_22825
COG3321 Polyketide synthase modules and related proteins.
  
 
 0.748
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.714
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.