STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LepB-2COG0681 Signal peptidase I. (135 aa)    
Predicted Functional Partners:
LepB-4
COG0681 Signal peptidase I.
  
  
 
0.915
RAM_20080
COG1132 ABC-type multidrug transport system, ATPase and permease components.
 
  
 0.905
LepB
COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
     
  0.900
LepB-3
COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
     
  0.900
RAM_20090
Hypothetical protein.
 
     0.879
RAM_20085
Hypothetical protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
     
 0.787
RAM_41845
TlpA-like family protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
 
   
 0.714
RAM_41850
Methylamine utilization protein MauE.
 
     0.591
RAM_41840
COG1132 ABC-type multidrug transport system, ATPase and permease components.
  
     0.584
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.574
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.