STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_20285Xylose isomerase; COG1082 Sugar phosphate isomerases/epimerases. (334 aa)    
Predicted Functional Partners:
RAM_20280
Oxidoreductase; COG0673 Predicted dehydrogenases and related proteins.
 
  
 0.962
RAM_20275
COG1879 ABC-type sugar transport system, periplasmic component.
 
    0.867
RbsC-4
COG4158 Predicted ABC-type sugar transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
 
    0.722
RAM_29970
Oxidoreductase domain-containing protein; COG0673 Predicted dehydrogenases and related proteins.
 
  
 0.620
RAM_08515
Oxidoreductase; COG0673 Predicted dehydrogenases and related proteins.
 
  
 0.570
IolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family.
  
  
 0.567
rifL
Oxidoreductase RifL; In a complex with RifK, RifL may catalyze the oxidation of UDP-glucose to UDP-3-keto-D-glucose, which would then be used by RifK to produce UDP-kanosamine. Is not able to use dTDP-glucose as substrate.
 
  
 0.540
RAM_22575
Oxidoreductase; COG0673 Predicted dehydrogenases and related proteins.
 
  
 0.527
IolB
5-deoxy-glucuronate isomerase; COG3718 Uncharacterized enzyme involved in inositol metabolism.
  
  
 0.506
RifS
NADH-dependent dihydrogenase; COG0673 Predicted dehydrogenases and related proteins.
 
  
 0.494
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.