STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LysA-2COG0019 Diaminopimelate decarboxylase. (431 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
 0.948
RAM_20500
3-oxoacyl-(ACP) synthase III.
 
    0.932
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
     
 0.906
RAM_35635
Tryptophan 2-monooxygenase; COG1231 Monoamine oxidase.
     
 0.811
KamA
COG1509 Lysine 2,3-aminomutase.
     
 0.807
RAM_20510
COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III.
     
 0.782
RAM_20595
Hypothetical protein; COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ).
 
     0.733
RAM_18460
Hypothetical protein; COG0439 Biotin carboxylase.
 
  
 0.731
RAM_18465
COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III.
 
    0.631
RAM_20515
COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
       0.601
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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