STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SuhB-4Myo-inositol-1(or 4)-monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (259 aa)    
Predicted Functional Partners:
RAM_47610
COG1260 Myo-inositol-1-phosphate synthase.
  
 
 0.937
IolG
Myo-inositol 2-dehydrogenase; COG0673 Predicted dehydrogenases and related proteins.
    
 0.907
PlcC
COG3511 Phospholipase C.
     
  0.900
PlcC-2
COG3511 Phospholipase C.
     
  0.900
PlcC-3
COG3511 Phospholipase C.
     
  0.900
hisF
Cyclase HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.776
hisA
COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.
  
  
 0.771
RAM_20670
COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
    0.690
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
  
 0.621
hisB
COG0131 Imidazoleglycerol-phosphate dehydratase.
  
  
 0.611
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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