close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_20720Non-ribosomal peptide synthetase/polyketide synthase; COG3321 Polyketide synthase modules and related proteins. (1798 aa)    
Predicted Functional Partners:
RAM_18760
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 0.999
RAM_18765
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
 0.999
RAM_27510
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
0.999
RAM_20005
Polyketide synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
0.981
FabH-2
COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III.
 
  
 0.953
RAM_31995
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
0.942
RAM_20715
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
 
0.937
RifB
COG3321 Polyketide synthase modules and related proteins.
 
 
0.931
RifA
Rifamycin polyketide synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
0.927
RAM_23445
COG3321 Polyketide synthase modules and related proteins; Belongs to the P-Pant transferase superfamily.
 
0.926
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (30%) [HD]