STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_20950Hypothetical protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes. (485 aa)    
Predicted Functional Partners:
NifU
Nitrogen fixation protein NifU; COG0822 NifU homolog involved in Fe-S cluster formation.
   
 
 0.757
ComE
Competence protein ComEC; COG0658 Predicted membrane metal-binding protein.
   
 
 0.599
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.590
RAM_20955
Large ATP-binding protein; COG5635 Predicted NTPase (NACHT family).
       0.564
RAM_10090
PA14 domain-containing protein; COG3209 Rhs family protein.
  
  
 0.539
RAM_23045
Two-component system sensor kinase; COG2770 FOG: HAMP domain.
 
 
 
 0.525
RAM_18760
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.524
RAM_18765
Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.524
RAM_27510
COG1020 Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.524
RAM_36280
COG1985 Pyrimidine reductase, riboflavin biosynthesis.
 
   
 0.504
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: low (22%) [HD]