STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBSIR2 family NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (297 aa)    
Predicted Functional Partners:
AcuC
Acetoin utilization protein AcuC; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
    
 0.753
RAM_06255
COG0210 Superfamily I DNA and RNA helicases.
  
 
 0.745
RAM_21435
Hypothetical protein.
       0.697
RAM_14595
COG1316 Transcriptional regulator.
  
    0.594
RAM_16700
COG2940 Proteins containing SET domain.
    
 0.576
RAM_29180
Hypothetical protein.
   
   0.570
MarR-2
COG1846 Transcriptional regulators.
   
    0.555
RAM_39425
Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.
 
 0.551
Lrp-5
COG1522 Transcriptional regulators.
  
    0.531
RAM_29585
ATPase; COG3903 Predicted ATPase.
   
    0.526
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
Server load: medium (50%) [HD]