STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TrxB-2COG0492 Thioredoxin reductase. (313 aa)    
Predicted Functional Partners:
RAM_06735
Hypothetical protein; COG0500 SAM-dependent methyltransferases.
 
    0.923
RAM_16320
Methyltransferase; COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis.
 
  
 0.868
RAM_21460
COG1396 Predicted transcriptional regulators.
 
    0.773
GlbN-2
Oxygen-binding heme protein; COG2346 Truncated hemoglobins.
  
    0.653
RAM_16325
COG1396 Predicted transcriptional regulators.
 
    0.508
MoeZ
Molybdopterin biosynthesis-like protein MoeZ; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
  
  
 0.461
TrxA
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.459
TrxA-2
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.459
RAM_13540
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.454
RAM_08135
COG3118 Thioredoxin domain-containing protein.
  
 
 0.447
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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