STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_21710Glycosyl transferase; COG0859 ADP-heptose:LPS heptosyltransferase. (347 aa)    
Predicted Functional Partners:
RAM_21715
HAD family hydrolase; COG0463 Glycosyltransferases involved in cell wall biogenesis.
   
 0.983
RAM_21755
D-beta-D-heptose 7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
 
  
 0.869
RAM_21795
COG0438 Glycosyltransferase.
 
  
 0.849
GmhA-3
COG0279 Phosphoheptose isomerase.
 
   
 0.848
RAM_21750
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
   
 0.835
RAM_21790
COG0438 Glycosyltransferase.
 
  
 0.784
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
   0.772
RAM_21765
Carbamoyltransferase; COG2192 Predicted carbamoyl transferase, NodU family.
 
  
 0.758
GmhA
COG0279 Phosphoheptose isomerase.
 
   
 0.747
GmhA-2
COG0279 Phosphoheptose isomerase.
 
   
 0.747
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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