STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GabD-2Succinate-semialdehyde dehydrogenase (NADP+); COG1012 NAD-dependent aldehyde dehydrogenases. (449 aa)    
Predicted Functional Partners:
BetA-2
COG2303 Choline dehydrogenase and related flavoproteins.
  
 
 0.690
BetA-3
COG2303 Choline dehydrogenase and related flavoproteins.
  
 
 0.690
BetA-4
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
  
 
 0.690
BetA-5
COG2303 Choline dehydrogenase and related flavoproteins.
  
 
 0.690
RAM_21710
Glycosyl transferase; COG0859 ADP-heptose:LPS heptosyltransferase.
 
   
 0.677
RAM_21715
HAD family hydrolase; COG0463 Glycosyltransferases involved in cell wall biogenesis.
 
   
 0.616
RAM_04490
COG1012 NAD-dependent aldehyde dehydrogenases.
 
    
0.541
RAM_21750
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.485
RAM_21725
Hypothetical protein.
       0.481
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.