STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_22180COG0247 Fe-S oxidoreductase. (700 aa)    
Predicted Functional Partners:
RAM_22175
Hypothetical protein.
       0.677
RAM_22185
FHA domain-containing protein; COG1716 FOG: FHA domain.
  
    0.526
RAM_22190
Hypothetical protein.
       0.522
FixA
COG2086 Electron transfer flavoprotein, beta subunit.
 
  
 0.465
FixB
COG2025 Electron transfer flavoprotein, alpha subunit.
 
  
 0.458
SdhB-3
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
 
 0.451
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
   
 0.444
RAM_22170
Oxidoreductase; COG0778 Nitroreductase.
       0.433
GapA
COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.430
RAM_45225
Hypothetical protein.
  
     0.411
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.