| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ComE | PilB | RAM_34315 | RAM_22665 | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | 0.862 |
| ComE | PilC | RAM_34315 | RAM_22660 | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | Type IV pilus assembly protein PilC; COG1459 Type II secretory pathway, component PulF. | 0.873 |
| ComE | PilD | RAM_34315 | RAM_22640 | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | Leader peptidase (prepilin peptidase)/N-methyltransferase; COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases. | 0.815 |
| ComE | PilD-2 | RAM_34315 | RAM_36470 | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | Leader peptidase (prepilin peptidase)/N-methyltransferase. | 0.779 |
| ComE | PilT | RAM_34315 | RAM_22670 | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | 0.777 |
| ComE | RAM_22650 | RAM_34315 | RAM_22650 | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | Hypothetical protein. | 0.735 |
| ComE | RAM_22655 | RAM_34315 | RAM_22655 | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | Hypothetical protein. | 0.735 |
| ComE | RAM_22675 | RAM_34315 | RAM_22675 | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | Type IV pilus assembly protein PilA. | 0.516 |
| ComE | Smf | RAM_34315 | RAM_09990 | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | DNA processing protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | 0.908 |
| PilB | ComE | RAM_22665 | RAM_34315 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | 0.862 |
| PilB | PilC | RAM_22665 | RAM_22660 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Type IV pilus assembly protein PilC; COG1459 Type II secretory pathway, component PulF. | 0.998 |
| PilB | PilD | RAM_22665 | RAM_22640 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Leader peptidase (prepilin peptidase)/N-methyltransferase; COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases. | 0.899 |
| PilB | PilD-2 | RAM_22665 | RAM_36470 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Leader peptidase (prepilin peptidase)/N-methyltransferase. | 0.533 |
| PilB | PilT | RAM_22665 | RAM_22670 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | 0.912 |
| PilB | RAM_22645 | RAM_22665 | RAM_22645 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Hypothetical protein. | 0.808 |
| PilB | RAM_22650 | RAM_22665 | RAM_22650 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Hypothetical protein. | 0.963 |
| PilB | RAM_22655 | RAM_22665 | RAM_22655 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Hypothetical protein. | 0.964 |
| PilB | RAM_22675 | RAM_22665 | RAM_22675 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | Type IV pilus assembly protein PilA. | 0.867 |
| PilB | Smf | RAM_22665 | RAM_09990 | COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. | DNA processing protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. | 0.639 |
| PilC | ComE | RAM_22660 | RAM_34315 | Type IV pilus assembly protein PilC; COG1459 Type II secretory pathway, component PulF. | Competence protein ComEC; COG0658 Predicted membrane metal-binding protein. | 0.873 |