STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_22780COG0520 Selenocysteine lyase. (399 aa)    
Predicted Functional Partners:
NifU
Nitrogen fixation protein NifU; COG0822 NifU homolog involved in Fe-S cluster formation.
 
 
 0.904
SufC
COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
 
  
 0.850
SufB
COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
 
 0.842
SufD
COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
 
 
 0.810
RAM_14405
COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.
 
  
 0.571
RAM_22785
Hypothetical protein.
       0.528
egtD
Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
  
  
 0.449
egtB
Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
  
  
 0.411
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.