STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAM_22905COG1925 Phosphotransferase system, HPr-related proteins. (92 aa)    
Predicted Functional Partners:
FruA
PTS system, fructose-specific IIBC component; COG1445 Phosphotransferase system fructose-specific component IIB.
 
 
 0.996
PtsI
COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria).
 
 0.996
PtsI-2
Phosphotransferase system EI component; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.992
FruB
PTS system, fructose-specific IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
 
 0.990
NagE-3
PTS system, glucose/maltose/N-acetylglucosamine-specific IIA component; COG2190 Phosphotransferase system IIA components.
 
 0.976
NagE
COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
 
 0.953
ManX-2
Mannose/sorbose-specific IIA subunit of PTS system; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.
  
 0.946
RAM_13850
Phosphocarrier protein.
  
  
 
0.904
FruK
1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.894
FruR-2
COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.813
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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