STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GipCOG3622 Hydroxypyruvate isomerase; Belongs to the hyi family. (276 aa)    
Predicted Functional Partners:
GarR
2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
 0.993
Gcl
COG3960 Glyoxylate carboligase; Belongs to the TPP enzyme family.
 
 
 0.990
GarR-2
2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
 0.966
RAM_09390
COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.915
RAM_13625
COG0665 Glycine/D-amino acid oxidases (deaminating).
  
  
  0.824
ApbA
2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase.
 
   
 0.616
RAM_23315
Formate dehydrogenase alpha subunit; COG3383 Uncharacterized anaerobic dehydrogenase.
 
     0.559
RAM_23305
Formate dehydrogenase, alpha subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.500
NuoF-2
COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
       0.500
AllB
L-hydantoinase/allantoinase; COG0044 Dihydroorotase and related cyclic amidohydrolases.
 
  
 0.497
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.