STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GclCOG3960 Glyoxylate carboligase; Belongs to the TPP enzyme family. (556 aa)    
Predicted Functional Partners:
Gip
COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 
 0.990
GarR
2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
 
 0.982
GarR-2
2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
 
 0.941
AceB
COG2225 Malate synthase; Belongs to the malate synthase family.
    
 0.918
AceB-2
COG2225 Malate synthase; Belongs to the malate synthase family.
    
 0.918
AceA
COG2224 Isocitrate lyase.
     
 0.914
RAM_09390
COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.906
CitE-2
COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
     
  0.900
Eda
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.
     
  0.900
Eda-2
COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.
     
  0.900
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.