STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PbuGMFS transporter xanthine/uracil permease; COG2252 Permeases. (481 aa)    
Predicted Functional Partners:
GlxK-2
COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family.
 
     0.803
RAM_23360
Hypothetical protein; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.
       0.776
RAM_01985
COG2233 Xanthine/uracil permeases.
 
  
 0.604
RAM_23370
COG1309 Transcriptional regulator.
       0.597
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
 0.544
RAM_23335
COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.
       0.530
GuaD
Deaminase; COG0590 Cytosine/adenosine deaminases.
       0.526
CoxS-3
COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.
       0.517
RAM_23345
COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.
       0.512
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
  
  
 0.488
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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