STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PbuGMFS transporter xanthine/uracil permease; COG2252 Permeases. (481 aa)    
Predicted Functional Partners:
GlxK-2
COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family.
 
     0.801
RAM_23360
Hypothetical protein; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.
       0.773
RAM_01985
COG2233 Xanthine/uracil permeases.
 
  
 0.611
RAM_23370
COG1309 Transcriptional regulator.
       0.597
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
 0.549
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.528
RAM_23335
COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.
     
 0.526
GuaD
Deaminase; COG0590 Cytosine/adenosine deaminases.
       0.521
RAM_23345
COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.
     
 0.516
purD
COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family.
  
  
 0.516
Your Current Organism:
Amycolatopsis mediterranei
NCBI taxonomy Id: 713604
Other names: A. mediterranei S699, Amycolatopsis mediterranei S699, Amycolatopsis mediterranei str. S699, Amycolatopsis mediterranei strain S699
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.